Endocrine Abstracts

Since 2011 trimethylamine N-oxide (TMAO) has been established as a cardiovascular risk biomarker in various patient populations. Previous studies have shown the association of TMAO levels with insulin resistance and diabetes. Additionally, a higher risk of cardiovascular events has been observed in patients with type 2 diabetes and higher levels of TMAO. However, the direct link between TMAO levels and kidney function in patients with diabetes is still unclear. Our objective w...

The polyglandular autoimmune syndromes (PAS) are rare disorders characterized as multiple autoimmune-mediated organ failure. PAS III includes chronic autoimmune thyroiditis with type 1 diabetes mellitus or pernicious anemia and/or vitiligo or alopecia and many other organ-specific autoimmune diseases, but never involves adrenal cortex. Several patients with PAS III and associated type 1 gastric neuroendocrine tumor (NET) have already been reported. We report probably the first...